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7.1  Discussion Materials & Extras

7 🌔 July 30, 2020

Chapter 11: Regulation of gene expression in bacteria and their viruses

In this chapter, you will learn how to:

  1. contrast positive and negative regulation of gene expression, and explain how both mechanisms control the activity of the lac operon.
  2. identify the trans-acting and cis-acting components of operons, and predict the effect of mutations in these components on gene expression.
  3. compare how simple molecules trigger changes in gene expression of different operons in bacteria.
  4. explain the roles of sequence-specific DNA-binding proteins and DNA regulatory sequences in coordinating the expression of sets of genes in bacteria and bacteriophage.

Chapter 12: Regulation of gene expression in eukaryotes

In this chapter, you will learn how to:

  1. compare and contrast the molecular mechanisms of gene regulation in eukaryotes and bacteria.
  2. explain how eukaryotes generate many different patterns of gene expression with a limited number of regulatory proteins.
  3. discuss the involvement of chromatin in eukaryotic gene regulation.
  4. describe the concept of epigenetic marks, and discuss how these can work in both DNA and proteins.
  5. compare and contrast the roles played by RNA molecules in repressing eukaryotic gene expression.

7.1  Discussion Materials & Extras

Homework problems:
[Blank: HW 7]
[Blank: HW 8]

Discussion notes: [Blank] | [Annotated]

Extras:
YouTube video on the lac operon.
YouTube video on the trp operon and attenuation.
YouTube video on gene regulation in eukaryotes.