7 🌔 July 30, 2020
Chapter 11: Regulation of gene expression in bacteria and their viruses
In this chapter, you will learn how to:
- contrast positive and negative regulation of gene expression, and explain how both mechanisms control the activity of the lac operon.
- identify the trans-acting and cis-acting components of operons, and predict the effect of mutations in these components on gene expression.
- compare how simple molecules trigger changes in gene expression of different operons in bacteria.
- explain the roles of sequence-specific DNA-binding proteins and DNA regulatory sequences in coordinating the expression of sets of genes in bacteria and bacteriophage.
Chapter 12: Regulation of gene expression in eukaryotes
In this chapter, you will learn how to:
- compare and contrast the molecular mechanisms of gene regulation in eukaryotes and bacteria.
- explain how eukaryotes generate many different patterns of gene expression with a limited number of regulatory proteins.
- discuss the involvement of chromatin in eukaryotic gene regulation.
- describe the concept of epigenetic marks, and discuss how these can work in both DNA and proteins.
- compare and contrast the roles played by RNA molecules in repressing eukaryotic gene expression.
7.1 Discussion Materials & Extras
Homework problems:
[Blank: HW 7]
[Blank: HW 8]
Discussion notes: [Blank] | [Annotated]
Extras:
YouTube video on the lac operon.
YouTube video on the trp operon and attenuation.
YouTube video on gene regulation in eukaryotes.