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2.1  Discussion Materials & Extras

2 🌒 June 25, 2020

Chapter 3: Independent assortment of genes

In this chapter, you will learn how to:

  1. design experiments to make a dihybrid and then self- or testcross it.
  2. analyze the progeny phenotypes of dihybrid selfs and testcrosses and, from these results, assess whether the two genes are assorting independently.
  3. in haploids, design experiments to make a transient diploid dihybrid AaBb and analyze its haploid progeny to assess whether the two genes are assorting independently.
  4. predict the genotypic ratios in meiotic products, genotypic ratios in progeny, and phenotypic ratios in progeny.
  5. use chi-square analysis to test whether observed phenotypic ratios are an acceptable fit to those predicted by independent assortment.
  6. design experiments to synthesize lines that are pure-breeding (homozygous) for two or more genes.
  7. interpret two-gene independent assortment ratios in terms of chromosome behavior at meiosis.
  8. analyze progeny ratios of dihybrids in terms of recombinant frequency (RF) and apply the diagnostic RF for independent assortment.
  9. extend the principles of two-gene independent assortment to heterozygotes for three or more genes, OR multiple genes that each contribute to a phenotype showing continuous distribution.

Chapter 4: Mapping eukaryote chromosomes by recombination

In this chapter, you will learn how to:

  1. perform a quantitative analysis of the progeny of a dihybrid testcross to assess whether or not the two genes are linked on the same chromosome.
  2. extend the same type of analysis to several loci to produce a map of the relative positions of loci on a chromosome.

2.1 Discussion Materials & Extras

Homework problems: [Blank]

Discussion notes: [Blank] | [Annotated]

Extra:
YouTube video on dihybrid crosses.
YouTube video on genetic recombination and gene mapping.
YouTube video with step-by-step 3-point testcross (including coefficient of coincidence and interference).